This is an advanced program in the refrigeration field. In this program, some research on the development and application of the non-pollution and energy- saving mixing refrigerant was conducted. Two kinds of refrigerant mixture (HFC152a/HCFC22 and HFC152a/HFC125) were proposed independently to substitute CFC12 and the domestic refrigerator with non-pollution and energy conversation was produced.
In this research, the thermodynamics principle on the choice of refrigerant alternatives was proposed. According to the experimental results of critical point track, the scientific foundation and practicability of using HFC152a/HCFC22 and HFC152a/HFC125 as a refrigerant of domestic refrigerator was demonstrated in theoretically. The thermodynamic properties and transport properties of new mixture refrigerants were studied experimentally and theoretically, and the first set of integrated and credible thermophysical property data, diagrams and table was obtained in the world. The working process of refrigeration system of the domestic refrigerator charged with new refrigerants and its main components were studied in detail. At the same time, the core technologies of production, such as the coherence with materials, flammability, explosibility, the performances of the compressor and the domestic refrigerator, foaming refrigerator case with pentamethylene, were also studied. On the basis of those researches, the mass-production of the non-pollution and energy-saving domestic refrigerators was realized through the trial production on the small- and middle-scale.
The small-scale trial production of the non-pollution and energy-saving domestic refrigerator charged with refrigerant HFC152a/HCFC22 was identified by the experts group of shaanxi province in 1990 and obtained the certification of the national science and technology achievement. The middle-scale trial production was checked and identified by the experts organized by the National Scientific Commission and  the Scientific Commission of Shaanxi province in December,1996. Their appraisement was very high, and they thought: Ў°the research achievement was creative and achieved international advanced level, and the research of basic thermophysical property of HFC152a/HCFC22 and industrialization of the domestic refrigerator also achieved the international leading levelЎ±. The industrialization production of the domestic refrigerator was imbursed by the foundation of Montreal Ozone Protection, and it was checked and accepted in 1997. The mass-production of the domestic refrigerator, whose refrigeration system is charged with the zerotropic mixing refrigerant, is a breakthrough. The development of the mixing refrigerant HFC152a/HFC125 and its application to the domestic refrigerator was conducted in 2000.
The achievement was applied to the production of the domestic refrigerator in the Chang-Ling (Group) Company Ltd. in April 1996, only three month later than developed country such as America and Japan, and solved the problem of alternative of CFC12 at the very low cost. Up to present, this company has produced more than 2.5 million domestic refrigerators charged with HFC152a/HCFC22. The increased profit was RMB Yuan 577.25 than before, and the average increased profit was RMB Yuan 96.208 million every year. The increased revenue was RMB Yuan 198.23 million and the average increased revenue was  RMB Yuan 33.038 million  every year.
After the substitute substance was put forward and the industrialization was realized, the mixing refrigerant constituted by HFC152a and HCFC22 have been also used in many corporations, such as Hai-Er, Mei-Ling, Hua-Ri Company. Every year the mixing refrigerant was consumed about 155 tons. This achievement has been extended and applied to the production of the domestic refrigerator in the Chang-Feng Bao-An Company Ltd in Gansu province.